Octet / Reactions
Friedel-Crafts Acylation
Included in Reactions.
Aromatic
Source Details
Id
friedel-crafts-acylation
Name
{
"en": "Friedel-Crafts Acylation",
"ar": "Friedel-Crafts Acylation",
"cs": "Friedel-Craftsova acylace",
"da": "Friedel-Crafts Acylering",
"de": "Friedel-Crafts Acylierung",
"el": "Ακυλίωση Friedel-Crafts",
"es-419": "Acylation de Friedel-Crafts",
"es-ES": "Acylation de Friedel-Crafts",
"es": "Acylation de Friedel-Crafts",
"fi": "Friedel-Crafts Asylointi",
"fr": "Acylation de Friedel-Crafts",
"he": "Friedel-Crafts Acylation",
"hr": "Friedel-Craftsova acilacija",
"hu": "Friedel-Crafts acilezés",
"id": "Asilasi Friedel-Crafts",
"it": "Acylation di Friedel-Crafts",
"ja": "Friedel-Craftsアシル化",
"ko": "Friedel-Crafts 아실화",
"lv": "Frīdela-Kraftsa acilēšana",
"nb": "Friedel-Crafts Acylering",
"nl": "Friedel-Crafts Acylering",
"pl": "Acylowanie Friedla-Craftsa",
"pt-BR": "Acylation de Friedel-Crafts",
"pt-PT": "Acylation de Friedel-Crafts",
"ro": "Acylation de Friedel-Crafts",
"ru": "Ацилирование Фриделя-Крафтса",
"sk": "Friedel-Craftsova acylácia",
"sl": "Friedel-Craftsova acilacija",
"sv": "Friedel-Crafts Acylering",
"th": "อะซิเลชันแบบ Friedel-Crafts",
"tr": "Friedel-Crafts açilolarakyüzerindeu",
"uk": "Ацилювання Фріделя-Крафтса",
"vi": "Acyl hóa Friedel-Crafts",
"zh-Hans": "Friedel-Crafts 酰基化",
"zh": "Friedel-Crafts 酰基化"
}Type
{
"en": "Aromatic",
"ar": "عطري",
"cs": "Aromatická",
"da": "Aromatisk",
"de": "Aromatisch",
"el": "Αρωματική",
"es-419": "Aromática",
"es-ES": "Aromática",
"es": "Aromática",
"fi": "Aromaattinen",
"fr": "Aromatique",
"he": "ארומטי",
"hr": "Aromatska",
"hu": "Aromás",
"id": "Aromatik",
"it": "Aromatica",
"ja": "芳香族",
"ko": "방향족",
"lv": "Aromātiska",
"nb": "Aromatisk",
"nl": "Aromatisch",
"pl": "Aromatyczna",
"pt-BR": "Aromática",
"pt-PT": "Aromática",
"ro": "Aromatică",
"ru": "Ароматические",
"sk": "Aromatická",
"sl": "Aromatska",
"sv": "Aromatisk",
"th": "อะโรมาติก",
"tr": "Aromatik",
"uk": "Ароматичні",
"vi": "Thơm",
"zh-Hans": "芳香族",
"zh": "芳香族"
}Subtype
{
"en": "Electrophilic Aromatic Substitution",
"ar": "استبدال عطري إلكتروفيلي",
"cs": "Elektrofilní aromatická substituce",
"da": "Elektrofil aromatisk substitution",
"de": "Elektrophile aromatische Substitution",
"el": "Ηλεκτρονιόφιλη αρωματική υποκατάσταση",
"es-419": "Sustitución aromática electrofílica",
"es-ES": "Sustitución aromática electrofílica",
"es": "Sustitución aromática electrofílica",
"fi": "Elektrofiilinen aromaattinen substituutio",
"fr": "Substitution aromatique électrophile",
"he": "התמרה ארומטית אלקטרופילית",
"hr": "Elektrofilna aromatska supstitucija",
"hu": "Elektrofil aromás szubsztitúció",
"id": "Substitusi aromatik elektrofilik",
"it": "Sostituzione aromatica elettrofila",
"ja": "求電子芳香族置換",
"ko": "친전자성 방향족 치환",
"lv": "Elektrofilā aromātiskā aizvietošana",
"nb": "Elektrofil aromatisk substitusjon",
"nl": "Elektrofiele aromatische substitutie",
"pl": "Elektrofilowa substytucja aromatyczna",
"pt-BR": "Substituição aromática eletrofílica",
"pt-PT": "Substituição aromática eletrofílica",
"ro": "Substituție aromatică electrofilă",
"ru": "Электрофильное ароматическое замещение",
"sk": "Elektrofilná aromatická substitúcia",
"sl": "Elektrofilna aromatska substitucija",
"sv": "Elektrofil aromatisk substitution",
"th": "การแทนที่อะโรมาติกแบบอิเล็กโทรฟิลิก",
"tr": "Elektrofilik aromatik sübstitüsyon",
"uk": "Електрофільне ароматичне заміщення",
"vi": "Thế thơm ái điện tử",
"zh-Hans": "亲电芳香取代",
"zh": "亲电芳香取代"
}Starting Material
c1ccccc1
Product
c1ccccc1C(=O)C
Reagents
CH₃COCl, AlCl₃
Mechanism
[
{
"smiles": "c1ccccc1",
"description": {
"en": "Benzene",
"ar": "بنزين",
"cs": "Benzen",
"da": "Benzen",
"de": "Benzol",
"el": "Βενζόλιο",
"es-419": "Benceno",
"es-ES": "Benceno",
"es": "Benceno",
"fi": "Bentseeni",
"fr": "Benzène",
"he": "בנזן",
"hr": "Benzen",
"hu": "Benzol",
"id": "Benzena",
"it": "Benzene",
"ja": "ベンゼン",
"ko": "벤젠",
"lv": "Benzols",
"nb": "Benzen",
"nl": "Benzeen",
"pl": "Benzen",
"pt-BR": "Benzeno",
"pt-PT": "Benzeno",
"ro": "Benzen",
"ru": "Бензол",
"sk": "Benzen",
"sl": "Benzen",
"sv": "Bensen",
"th": "เบนซีน",
"tr": "Benzen",
"uk": "Бензен",
"vi": "Benzen",
"zh-Hans": "苯",
"zh": "苯"
}
},
{
"smiles": "c1ccccc1",
"description": {
"en": "AlCl₃ + RCOCl → RCO⁺ (acylium ion)",
"ar": "AlCl₃ + RCOCl → RCO⁺ (acylium أيون)",
"cs": "AlCl₃ + RCOCl → RCO⁺ (acyliový ion)",
"da": "AlCl₃ + RCOCl → RCO⁺ (acyliumion)",
"de": "AlCl₃ + RCOCl → RCO⁺ (Acyliumion)",
"el": "AlCl₃ + RCOCl → RCO⁺ (acylium iσε)",
"es-419": "AlCl₃ + RCOCl → RCO⁺ (ion acilio)",
"es-ES": "AlCl₃ + RCOCl → RCO⁺ (ion acilio)",
"es": "AlCl₃ + RCOCl → RCO⁺ (ion acilio)",
"fi": "AlCl₃ + RCOCl → RCO⁺ (asyyliumioni)",
"fr": "AlCl₃ + RCOCl → RCO⁺ (ion acylium)",
"he": "AlCl₃ + RCOCl → RCO⁺ (acylium יון)",
"hr": "AlCl₃ + RCOCl → RCO⁺ (acilijev ion)",
"hu": "AlCl₃ + RCOCl → RCO⁺ (acylium ion)",
"id": "AlCl₃ + RCOCl → RCO⁺ (ion asilum)",
"it": "AlCl₃ + RCOCl → RCO⁺ (ione acilio)",
"ja": "AlCl₃ + RCOCl → RCO⁺（アシリウムイオン）",
"ko": "AlCl₃ + RCOCl → RCO⁺(아실륨 이온)",
"lv": "AlCl₃ + RCOCl → RCO⁺ (acylium jons)",
"nb": "AlCl₃ + RCOCl → RCO⁺ (acyliumion)",
"nl": "AlCl₃ + RCOCl → RCO⁺ (acyliumion)",
"pl": "AlCl₃ + RCOCl → RCO⁺ (acylium jon)",
"pt-BR": "AlCl₃ + RCOCl → RCO⁺ (íon acílio)",
"pt-PT": "AlCl₃ + RCOCl → RCO⁺ (íon acílio)",
"ro": "AlCl₃ + RCOCl → RCO⁺ (ion aciliu)",
"ru": "AlCl₃ + RCOCl → RCO⁺ (acylium ион)",
"sk": "AlCl₃ + RCOCl → RCO⁺ (acýliový ión)",
"sl": "AlCl₃ + RCOCl → RCO⁺ (acilijev ion)",
"sv": "AlCl₃ + RCOCl → RCO⁺ (acyliumjon)",
"th": "AlCl₃ + RCOCl → RCO⁺ (ไอออนอะซิลเลียม)",
"tr": "AlCl₃ + RCOCl → RCO⁺ (acylium iüzerinde)",
"uk": "AlCl₃ + RCOCl → RCO⁺ (acylium іон)",
"vi": "AlCl₃ + RCOCl → RCO⁺ (ion acylium)",
"zh-Hans": "AlCl₃ + RCOCl → RCO⁺（酰鎓离子）",
"zh": "AlCl₃ + RCOCl → RCO⁺（酰鎓离子）"
}
},
{
"smiles": "c1ccccc1C(=O)C",
"description": {
"en": "Acetophenone",
"ar": "أسيتوفينون",
"cs": "Acetofenon",
"da": "Acetophenone",
"de": "Acetophenone",
"el": "Acetophenένα",
"es-419": "Acetophenone",
"es-ES": "Acetophenone",
"es": "Acetophenone",
"fi": "Acetophenone",
"fr": "Acetophenone",
"he": "אצטופנון",
"hr": "Acetofenon",
"hu": "Acetophenegy",
"id": "Asetofenon",
"it": "Acetophenone",
"ja": "アセトフェノン",
"ko": "아세토페논",
"lv": "Acetofenons",
"nb": "Acetophenone",
"nl": "Acetophenone",
"pl": "Acetofenon",
"pt-BR": "Acetophenone",
"pt-PT": "Acetophenone",
"ro": "Acetophenone",
"ru": "Ацетофенон",
"sk": "Acetofenon",
"sl": "Acetofenon",
"sv": "Acetophenone",
"th": "อะเซโทฟีโนน",
"tr": "Acetophenbir",
"uk": "Ацетофенон",
"vi": "Acetophenone",
"zh-Hans": "苯乙酮",
"zh": "苯乙酮"
}
}
]Tips
[
{
"en": "Acylium ion resonance-stabilized → NO rearrangement",
"ar": "Acylium أيون resonance-stabilized → NO إعادة ترتيب",
"cs": "Acylium ion resonance-stabilized → NO presmyk",
"da": "Acyliumion resonansstabiliseret → INGEN omlejring",
"de": "Acyliumion resonanzstabilisiert → KEINE Umlagerung",
"el": "Acylium iσε resσεance-stabilized → NO αναδιάταξη",
"es-419": "Acylium ion estabilizado por resonancia → Sin reordenamiento",
"es-ES": "Acylium ion estabilizado por resonancia → Sin reordenamiento",
"es": "Acylium ion estabilizado por resonancia → Sin reordenamiento",
"fi": "Asyyliumioni resonanssistabiloitu → EI uudelleenjärjestymistä",
"fr": "Acylium ion stabilisé par résonance → Pas de réarrangement",
"he": "Acylium יון resonance-stabilized → NO סידור מחדש",
"hr": "Acylium ion resonance-stabilized → NO pregrađivanje",
"hu": "Acylium ion resonance-stabilized → NO átrendeződés",
"id": "Ion asilum distabilkan resonansi → TIDAK ada penataan ulang",
"it": "Acylium ion stabilizzato per risonanza → Nessun riarrangiamento",
"ja": "アシリウムイオンは共鳴安定化される → 転位なし",
"ko": "아실륨 이온은 공명 안정화됨 → 재배열 없음",
"lv": "Acylium jons resonance-stabilized → NO pargrupesanas",
"nb": "Acyliumion resonansstabilisert → INGEN omleiring",
"nl": "Acyliumion resonantiegestabiliseerd → GEEN omlegging",
"pl": "Acylium jon resonance-stabilized → NO przegrupowanie",
"pt-BR": "Acylium ion estabilizado por ressonância → Sem rearranjo",
"pt-PT": "Acylium ion estabilizado por ressonância → Sem rearranjo",
"ro": "Acylium ion stabilizat prin rezonanță → Fără rearanjare",
"ru": "Acylium ион resonance-stabilized → NO перегруппировка",
"sk": "Acylium ion resonance-stabilized → NO prestavba",
"sl": "Acylium ion resonance-stabilized → NO preureditev",
"sv": "Acyliumjon resonansstabiliserad → INGEN omlagring",
"th": "ไอออนอะซิลเลียมเสถียรด้วยเรโซแนนซ์ → ไม่มีการจัดเรียงใหม่",
"tr": "Acylium iüzerinde resüzerindeance-stabilized → NO yeniden düzenlenme",
"uk": "Acylium іон resonance-stabilized → NO перегрупування",
"vi": "Ion acylium được bền hóa cộng hưởng → KHÔNG tái sắp xếp",
"zh-Hans": "酰鎓离子受共振稳定 → 不重排",
"zh": "酰鎓离子受共振稳定 → 不重排"
},
{
"en": "Product is deactivated → only monosubstitution",
"ar": "الناتج هو معطّل → فقط monosubstitution",
"cs": "Produkt je deactivated → only monosubstitution",
"da": "Produkt er deactivated → only monosubstitution",
"de": "Produkt ist deactivated → only monosubstitution",
"el": "Προϊόν is deενεργοποιημένο → μόνο moόχιsubstitutiσε",
"es-419": "Producto es deactivated → only monosubstitution",
"es-ES": "Producto es deactivated → only monosubstitution",
"es": "Producto es deactivated → only monosubstitution",
"fi": "Tuote on deactivated → only monosubstitution",
"fr": "Produit est deactivated → only monosubstitution",
"he": "תוצר הוא מושבת → רק monosubstitution",
"hr": "Produkt je deactivated → only monosubstitution",
"hu": "Termék is deaktivált → csak monbancssubstitution",
"id": "Produk dinonaktifkan → hanya monosubstitusi",
"it": "Prodotto è deactivated → only monosubstitution",
"ja": "生成物は不活性化される → 一置換のみ",
"ko": "생성물이 비활성화되어 단일 치환만 일어남",
"lv": "Produkts ir deactivated → only monosubstitution",
"nb": "Produkt er deactivated → only monosubstitution",
"nl": "Product is gedeactiveerd → alleen monosubstitutie",
"pl": "Produkt jest deactivated → only monosubstitution",
"pt-BR": "Produto é deactivated → only monosubstitution",
"pt-PT": "Produto é deactivated → only monosubstitution",
"ro": "Produs este deactivated → only monosubstitution",
"ru": "Продукт является deactivated → only monosubstitution",
"sk": "Produkt je deactivated → only monosubstitution",
"sl": "Produkt je deactivated → only monosubstitution",
"sv": "Produkt är deactivated → only monosubstitution",
"th": "ผลิตภัณฑ์ถูกลดความไว →...Related Reactions
friedel-crafts-alkylation, clemmensen-reduction
Is Free
true