Octet / Reactions
Sonogashira Coupling
Included in Reactions.
Coupling
Source Details
Id
sonogashira-coupling
Name
{
"en": "Sonogashira Coupling",
"ar": "Sonogashira ازدواج",
"cs": "Sonogashira Kopulace",
"da": "Sonogashira Kobling",
"de": "Sonogashira Kupplung",
"el": "Σύζευξη Soόχιgωςhira",
"es-419": "Acoplamiento de Sonogashira",
"es-ES": "Acoplamiento de Sonogashira",
"es": "Acoplamiento de Sonogashira",
"fi": "Sonogashira Kytkentä",
"fr": "Couplage de Sonogashira",
"he": "Sonogashira צימוד",
"hr": "Sonogashira Sprezanje",
"hu": "Sonbancsgminthira-kapcsolás",
"id": "Kopling Sonogashira",
"it": "Accoppiamento di Sonogashira",
"ja": "Sonogashiraカップリング",
"ko": "Sonogashira 커플링",
"lv": "Sonogashira Savienosana",
"nb": "Sonogashira Kobling",
"nl": "Sonogashira Koppeling",
"pl": "Sonogashira Sprzeganie",
"pt-BR": "Acoplamento de Sonogashira",
"pt-PT": "Acoplamento de Sonogashira",
"ro": "Cuplare de Sonogashira",
"ru": "Sonogashira Сочетание",
"sk": "Sonogashira Spajanie",
"sl": "Sonogashira Sklopitev",
"sv": "Sonogashira Koppling",
"th": "คัปปลิงแบบ Sonogashira",
"tr": "Soyokgolarakhira eşleşmesi",
"uk": "Sonogashira Сполучення",
"vi": "Ghép Sonogashira",
"zh-Hans": "Sonogashira 偶联",
"zh": "Sonogashira 偶联"
}Type
{
"en": "Coupling",
"ar": "اقتران",
"cs": "Párování",
"da": "Kobling",
"de": "Kupplung",
"el": "Σύζευξη",
"es-419": "Acoplamiento",
"es-ES": "Acoplamiento",
"es": "Acoplamiento",
"fi": "Kytkentä",
"fr": "Couplage",
"he": "צימוד",
"hr": "Spajanje",
"hu": "Kapcsolás",
"id": "Kopling",
"it": "Accoppiamento",
"ja": "カップリング",
"ko": "짝지음",
"lv": "Sakabe",
"nb": "Kobling",
"nl": "Koppeling",
"pl": "Sprzęganie",
"pt-BR": "Acoplamento",
"pt-PT": "Acoplamento",
"ro": "Cuplare",
"ru": "Сочетание",
"sk": "Spájanie",
"sl": "Spajanje",
"sv": "Koppling",
"th": "คัปปลิง",
"tr": "Eşleşme",
"uk": "Сполучення",
"vi": "Ghép cặp",
"zh-Hans": "偶联",
"zh": "偶联"
}Starting Material
c1ccccc1Br
Product
c1ccccc1C#CC
Reagents
Terminal alkyne, Pd catalyst, CuI (co-catalyst), amine base
Mechanism
[
{
"smiles": "c1ccccc1Br",
"description": {
"en": "Aryl halide",
"ar": "أريل هاليد",
"cs": "Aryl halogenid",
"da": "Aryl halid",
"de": "Aryl Halogenid",
"el": "Aryl αλογονίδιο",
"es-419": "Aryl haluro",
"es-ES": "Aryl haluro",
"es": "Aryl haluro",
"fi": "Aryl halidi",
"fr": "Aryl halogénure",
"he": "אריל הליד",
"hr": "Aril halogenid",
"hu": "Aryl halogenid",
"id": "Aril halida",
"it": "Aryl alogenuro",
"ja": "アリールハライド",
"ko": "아릴 할라이드",
"lv": "Aril halogenids",
"nb": "Aryl halid",
"nl": "Arylhalogenide",
"pl": "Aryl halogenek",
"pt-BR": "Aryl haleto",
"pt-PT": "Aryl haleto",
"ro": "Aryl halogenură",
"ru": "Арил галогенид",
"sk": "Aryl halogenid",
"sl": "Aril halogenid",
"sv": "Aryl halid",
"th": "อะริลเฮไลด์",
"tr": "Aryl halojenür",
"uk": "Арил галогенід",
"vi": "Halogenua aryl",
"zh-Hans": "芳基卤化物",
"zh": "芳基卤化物"
}
},
{
"smiles": "C#CC",
"description": {
"en": "Terminal alkyne (propyne)",
"ar": "ألكاين طرفي (propyne)",
"cs": "Terminalni alkyn (propyne)",
"da": "Terminal alkyn (propyn)",
"de": "terminales Alkin (Propin)",
"el": "Termσεal αλκίνιο (propyne)",
"es-419": "Alquino terminal (propyne)",
"es-ES": "Alquino terminal (propyne)",
"es": "Alquino terminal (propyne)",
"fi": "Terminaalinen alkyyni (propyyni)",
"fr": "Alcyne terminal (propyne)",
"he": "אלקין קצה (propyne)",
"hr": "Terminalni alkin (propyne)",
"hu": "Termbanal alkban (propyne)",
"id": "Alkuna terminal (propuna)",
"it": "Alchino terminale (propyne)",
"ja": "末端アルキン（プロピン）",
"ko": "말단 알카인(프로파인)",
"lv": "Terminalais alkins (propyne)",
"nb": "Terminal alkyn (propyn)",
"nl": "Terminaal alkyn (propyn)",
"pl": "Terminalny alkin (propyne)",
"pt-BR": "Alcino terminal (propyne)",
"pt-PT": "Alcino terminal (propyne)",
"ro": "Alchină terminală (propyne)",
"ru": "Терминальный алкин (propyne)",
"sk": "Terminalny alkyn (propyne)",
"sl": "Terminalni alkin (propyne)",
"sv": "Terminal alkyn (propyn)",
"th": "แอลไคน์ปลายสาย (โพรไพน์)",
"tr": "Termiçindeal alkiçinde (propyne)",
"uk": "Термінальний алкін (propyne)",
"vi": "Ankyn đầu mạch (propyne)",
"zh-Hans": "端炔（丙炔）",
"zh": "端炔（丙炔）"
}
},
{
"smiles": "c1ccccc1C#CC",
"description": {
"en": "Aryl-substituted alkyne",
"ar": "Aryl-substituted ألكاين",
"cs": "Aryl-substituovany alkyn",
"da": "Aryl-substitueret alkyne",
"de": "Aryl-substituiert alkyne",
"el": "Aryl-υποκατεστημένο αλκίνιο",
"es-419": "Aryl-substituted alquino",
"es-ES": "Aryl-substituted alquino",
"es": "Aryl-substituted alquino",
"fi": "Aryl-substituoitu alkyne",
"fr": "Aryl-substituted alcyne",
"he": "Aryl-substituted אלקין",
"hr": "Aril-supstituiran alkin",
"hu": "Aryl-szubsztituált alkban",
"id": "Alkuna tersubstitusi aril",
"it": "Aryl-substituted alchino",
"ja": "アリール置換アルキン",
"ko": "아릴 치환 알카인",
"lv": "Aril-aizvietots alkins",
"nb": "Aryl-substituert alkyne",
"nl": "Aryl-gesubstitueerd alkyne",
"pl": "Aryl-podstawiony alkin",
"pt-BR": "Aryl-substituted alcino",
"pt-PT": "Aryl-substituted alcino",
"ro": "Aryl-substituted alchină",
"ru": "Арил-замещенный алкин",
"sk": "Aryl-substituovany alkyn",
"sl": "Aril-substituiran alkin",
"sv": "Aryl-substituerad alkyne",
"th": "แอลไคน์ที่ถูกแทนที่ด้วยอะริล",
"tr": "Aryl-sübstitüe alkiçinde",
"uk": "Арил-заміщений алкін",
"vi": "Ankyn thế aryl",
"zh-Hans": "芳基取代炔烃",
"zh": "芳基取代炔烃"
}
}
]Tips
[
{
"en": "Aryl halide + Terminal alkyne → Aryl alkyne",
"ar": "أريل هاليد + ألكاين طرفي → أريل ألكاين",
"cs": "Aryl halogenid + Terminalni alkyn → Aryl alkyn",
"da": "Aryl halid + Terminal alkyne → Aryl alkyne",
"de": "Aryl Halogenid + Terminal alkyne → Aryl alkyne",
"el": "Aryl αλογονίδιο + Termσεal αλκίνιο → Aryl αλκίνιο",
"es-419": "Aryl haluro + Alquino terminal → Aryl alquino",
"es-ES": "Aryl haluro + Alquino terminal → Aryl alquino",
"es": "Aryl haluro + Alquino terminal → Aryl alquino",
"fi": "Aryl halidi + Terminal alkyne → Aryl alkyne",
"fr": "Aryl halogénure + Alcyne terminal → Aryl alcyne",
"he": "אריל הליד + אלקין קצה → אריל אלקין",
"hr": "Aril halogenid + Terminalni alkin → Aril alkin",
"hu": "Aryl halogenid + Termbanal alkban → Aryl alkban",
"id": "Aril halida + alkuna terminal → aril alkuna",
"it": "Aryl alogenuro + Alchino terminale → Aryl alchino",
"ja": "アリールハライド + 末端アルキン → アリールアルキン",
"ko": "아릴 할라이드 + 말단 알카인 → 아릴 알카인",
"lv": "Aril halogenids + Terminalais alkins → Aril alkins",
"nb": "Aryl halid + Terminal alkyne → Aryl alkyne",
"nl": "Arylhalogenide + Terminaal alkyn → Aryl alkyne",
"pl": "Aryl halogenek + Terminalny alkin → Aryl alkin",
"pt-BR": "Aryl haleto + Alcino terminal → Aryl alcino",
"pt-PT": "Aryl haleto + Alcino terminal → Aryl alcino",
"ro": "Aryl halogenură + Alchină terminală → Aryl alchină",
"ru": "Арил галогенид + Терминальный алкин → Арил алкин",
"sk": "Aryl halogenid + Terminalny alkyn → Aryl alkyn",
"sl": "Aril halogenid + Terminalni alkin → Aril alkin",
"sv": "Aryl halid + Terminal alkyne → Aryl alkyne",
"th": "อะริลเฮไลด์ + แอลไคน์ปลายสาย → อะริลแอลไคน์",
"tr": "Aryl halojenür + Termiçindeal alkiçinde → Aryl alkiçinde",
"uk": "Арил галогенід + Термінальний алкін → Арил алкін",
"vi": "Halogenua aryl + alkyn đầu mạch → aryl alkyn",
"zh-Hans": "芳基卤化物 + 端炔 → 芳基炔烃",
"zh": "芳基卤化物 + 端炔 → 芳基炔烃"
},
{
"en": "Cu activates alkyne for transmetalation",
"ar": "Cu ينشّط ألكاين لـ transmetalation",
"cs": "Cu aktivuje alkyn pro transmetalation",
"da": "Cu aktiverer alkyne for transmetalation",
"de": "Cu aktiviert alkyne for transmetalation",
"el": "Cu ενεργοποιεί αλκίνιο για transmetalσεiσε",
"es-419": "Cu activates alquino para transmetalation",
"es-ES": "Cu activates alquino para transmetalation",
"es": "Cu activates alquino para transmetalation",
"fi": "Cu aktivoi alkyne for transmetalation",
"fr": "Cu activates alcyne pour transmetalation",
"he": "Cu מפעיל אלקין עבור transmetalation",
"hr": "Cu aktivira alkin za transmetalation",
"hu": "Cu aktivál alkban számára transmetalnálion",
"id": "Cu mengaktifkan alkuna untuk transmetaliasi",
"it": "Cu activates alchino per transmetalation",
"ja": "Cuがアルキンをトランスメタル化に向けて活性化する",
"ko": "Cu가 알카인을 활성화하여 트랜스금속화를 돕음",
"lv": "Cu aktivizē alkins prieks transmetalation",
"nb": "Cu aktiverer alkyne for transmetalation",
"nl": "Cu activeert alkyne for transmetalation",
"pl": "Cu aktywuje alkin dla transmetalation",
"pt-BR": "Cu activates alcino para transmetalation",
"pt-PT": "Cu activates alcino para transmetalation",
"ro": "Cu activates alchină pentru transmetalation",
"ru": "Cu активирует алкин для transmetalation",
"sk": "Cu aktivuje alkyn pre transmetalation",
"sl": "Cu aktivira alkin za transmetalation",
"sv": "Cu aktiverar alkyne for transmetalation",
"th": "Cu กระตุ้นแอลไคน์สำหรับการถ่ายโอนโลหะ",
"tr": "Cu aktive eder alkiçinde içiçinde transmetaldeiüzerinde",
"uk": "Cu активує алкін для transmetalation",
"vi": "Cu hoạt hóa alkyn cho chuyển kim loại",
"zh-Hans": "Cu 活化炔烃以进行转金属化",
"zh": "Cu 活化炔烃以进行转金属化"
},
{
"en": "Room temperature, mild conditions",
"ar": "Room درجة الحرارة, شروط لطيفة",
"cs": "pokojova teplota, mirny podminky",
"da": "Stuetemperatur, mild condit...Related Reactions
suzuki-coupling, heck-reaction
Is Free
false